Short Course:
Biostatistics Case Studies 2018
Liu Research Center (Bldg. RB3)-Room.138 or
CDCRC Conference Room (104 & 105), LABioMed at
Harbor-UCLA Medical Center
Class Web Page: http://research.labiomed.org /biostat
Contact: Youngju Pak,
Ph.D.
Tel: 310-222-1874
Course details follow. This course is a journal
club-style discussion of statistical issues using published biomedical research
articles, both clinical and/or basic science studies, depending on participant
interest. A particular inferential problem and its statistical solution from
each article will be our focus and topic of discussion. The discussion will be
on the logical basis for the chosen methods, rather than mathematical details.
Current
Schedule:
Date |
Topic |
Session 1 Tuesday Aug. 14 CDCRC Conference Room(104 & 105) |
Understanding
hypothesis testing, P values, and sample size determination. Effect of Lower Targets for Blood Pressure and LDL Cholesterol
on Atherosclerosis in Diabetes: The SANDS Randomized Trial, JAMA 2008;99(14):1678-89 |
Session 2 Tuesday RB-3 Conference Room(Rm.138) Guest Lecturer: Liz Chen, MBA |
Overview of Study
Designs. Plasma Proportion convertase subtilisin/kexin type 9 levels and the risk of first
cardiovascular events, European Heart Journal 2015; Oct;554-60. Effect of potentially modifiable risk factors associated with
myocardial infarction in 52 countries (the INTERHEART study): case-control
study, Lancet 2004 364(9438):937-52. |
Session 3 Tuesday RB-3 Conference Room(Rm.138) |
REDCap (Research Electronic Data Capture)
101. Effectiveness
of a smartphone application for weight loss compared to usual care in
overweight primary care patients: a randomized controlled trial. Ann Intern
Med 2014; 161(10 0): S5–12. |
Session 4 Tuesday RB-3 Conference Room(Rm.138) |
Regression Models
and Multivariate Analyses Elevated Plasma
Level of Visfatin/Pro-B Cell Colony-Enhancing
Factor in Patients with Type 2 Diabetes Mellitus, JCEM 2006 91(1):295-9 |
Session 5 Tuesday Sept. 11 CDCRC Conference Room(104 & 105) |
Adaptive Designs in
Clinical Trials. Randomized Phase II Study of Gemcitabine and Docetaxel
Compared with Gemcitabine Alone in Patients with Metastatic Soft Tissue
Sarcomas: Results of Sarcoma alliance for Research Through Collaboration
Study 002, J Clin Oncol.
2007 Aug 20;25(24):3790. Session Slides |
Session 6 Tuesday Sept. 18 RB-3 Conference Room(Rm.138) Guest Lecturer :Xiuqing Guo, Ph.D. |
Genetic Study of
Common Diseases: Genome Wide Association Study, Meta-analysis, Trans-Ethnic
Study, Clinical and Biological Relevance of GWAS Loci. Biological, Clinical and Population Relevance of 95 Loci for
Blood Lipids, Nature 2010 446(7307):707-713 |