Short Course: Biostatistics Case Studies
2017
Liu Research Center
(Bldg. RB3)-Room.138 or CDCRC Conference Room (104 & 105), LABioMed
at Harbor-UCLA Medical Center
Class Web Page: http://research.labiomed.org
/biostat
Contact: Youngju Pak, Ph.D.
Tel: 310-222-1874
Course details follow. This course is a journal
club-style discussion of statistical issues using published biomedical research
articles, both clinical and/or basic science studies, depending on participant
interest. A particular inferential problem and its statistical solution from
each article will be our focus and topic of discussion. The discussion will be
on the logical basis for the chosen methods, rather than mathematical details.
Current
Schedule:
|
Date |
Topic |
|
Session 1 Tuesday Aug. 15 RB-3 Conference Room(Rm.138) |
Understanding
hypothesis testing, P values, and sample size determination. Effect of Lower Targets for Blood
Pressure and LDL Cholesterol on Atherosclerosis in Diabetes: The SANDS
Randomized Trial, JAMA 2008;99(14):1678-89 |
|
Session 2 Tuesday RB-3 Conference Room(Rm.138) Guest Lecturer: Liz Chen, MBA |
REDCap (Research Electronic Data Capture)
101. Effectiveness of a smartphone application for weight loss
compared to usual care in overweight primary care patients: a randomized
controlled trial. Ann Intern Med 2014; 161(10 0): S5–12. |
|
Session 3 Tuesday RB-3 Conference Room(Rm.138) |
Overview of Study
Designs. Plasma Proportion convertase subtilisin/kexin type 9
levels and the risk of first cardiovascular events, European Heart Journal
2015; Oct;554-60. Effect of potentially modifiable
risk factors associated with myocardial infarction in 52 countries (the
INTERHEART study): case-control study, Lancet 2004 364(9438):937-52. |
|
Session 4 Tuesday RB-3 Conference Room(Rm.138) |
How to interpret
Bayesian Analysis and Results? Surgical or Transcatheter
Aortic-Valve Replacement in intermediate-Risk Patients, N ENGL J MED 376:14,
Apr 16,2017 |
|
Session 5 Tuesday Sept. 12 CDCRC Conference Room(104 & 105) Guest Lecturer :Xiuqing Guo, Ph.D. |
Genetic Study of Common
Diseases: Genome Wide Association Study, Meta-analysis, Trans-Ethnic Study,
Clinical and Biological Relevance of GWAS Loci. Biological, Clinical and Population
Relevance of 95 Loci for Blood Lipids, Nature 2010 446(7307):707-713 |
|
Session 6 Tuesday Sept. 19 RB-3 Conference Room(Rm.138) |
Adaptive Designs in Clinical Trials. Randomized Phase II Study of
Gemcitabine and Docetaxel Compared with Gemcitabine Alone in Patients with
Metastatic Soft Tissue Sarcomas: Results of Sarcoma alliance for Research
Through Collaboration Study 002, J Clin Oncol. 2007 Aug 20;25(24):3790. Session Slides |